| Product Name | Dihydromyricetin Powder |
| Grade | Food Grade |
| Certification | HACCP/ISO 22000/HALAL/IS0 9001 |
| Specification | 99%Pure |
| Appearance | White Fine |
| Delivery Time | 7 days |
| Nutrient Content | Vegan, Gluten-Free, Non-GMO, Natural |
| Shelf Life | 2 Years |
| Storage | Cool Dry Place |
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Unique Alcohol Metabolism Modulation with Liver-Protective Mechanism
Enhances Alcohol Breakdown: DHM upregulates alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH2), reducing blood acetaldehyde levels by 40–60% (in preclinical models), which alleviates hangover symptoms (headache, nausea).
Liver Protection: It inhibits hepatic lipid peroxidation (MDA reduction by 35%) and activates Nrf2 antioxidant pathways, protecting hepatocytes from alcohol-induced damage. This makes it a prime ingredient in liver health and hangover relief supplements, differentiating it from generic antioxidants.
Potent Antioxidant & Anti-Inflammatory Properties
Free Radical Scavenging: DHM exhibits an ORAC value of ~28,000 μmol/g, surpassing many common flavonoids (e.g., quercetin). It neutralizes hydroxyl radicals (EC₅₀ = 1.2 μM) and inhibits NF-κB-mediated inflammation, addressing oxidative stress in conditions like metabolic syndrome.
Neuroprotective Effects: Preclinical studies show DHM crosses the blood-brain barrier to reduce Aβ aggregation and tau phosphorylation, positioning it for anti-aging and cognitive support formulations.
Sourcing Exclusivity & Botanical Rarity
Primary Botanical Source: Ampelopsis grossedentata thrives in subtropical regions of China (e.g., Hunan, Guangxi), where wild populations are sustainably harvested. Cultivated varieties undergo controlled pruning to maintain DHM content (often ≥98% in purified extracts), giving suppliers a monopoly on high-purity sourcing.
Low Market Saturation: Compared to mainstream flavonoids (hesperidin, catechins), DHM’s niche botanical origin reduces competition, enabling premium pricing (2–3x higher than standard flavonoid extracts).
Clinical Validation & Emerging Research Support
Human Studies: A 2022 clinical trial showed 500 mg DHM reduced hangover severity scores by 42% compared to placebo. Another study linked DHM supplementation (300 mg/day) to a 15% decrease in ALT/AST liver enzymes in heavy drinkers.
Expanding Applications: Research highlights DHM’s potential in:
Obesity (inhibits adipogenesis in 3T3-L1 cells)
Type 2 diabetes (improves insulin sensitivity in preclinical models)
Alcohol use disorder (reduces ethanol consumption in animal addiction models).
Established in 2006, we are a certified OEM/ODM manufacturer specializing in premium health supplements. Holding NSF-GMP,HACCP, ISO 22000, USDA Organic, EU Organic, Halal, and FDA certifications, our facility integrates advanced technologies for tablet, capsule, powder, gummy, and softgel production. From formulation to packaging, we provide full-cycle solutions with strict quality protocols, including raw material traceability, third-party lab testing, and Halal-compliant dedicated lines. Serving global markets including North America, Europe, and Asia, we prioritize sustainability through eco-friendly processes and transparent labeling. With 19+ years of expertise, we empower brands to deliver scientifically validated, certification-backed nutraceuticals tailored to diverse regulatory and cultural requirements 
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