
Introduction:
Senna belongs to a large genus of flowering plants found throughout the tropics, commonly used species being Cassia acutifolio (Alexandrian senna) and C. angustifolio (Indian or Tinnevelly senna). Extracts of the leaves, flowers and fruit of senna have been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components in senna extracts are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.
Function
1. Cathartic effect: senna infusion contains anthraquinone derivatives, its cathartic effect and irritation more than other laxatives.
2. Antibacterial inhibition: senna extract alcohol resistant variety of bacteria such as staphylococcus, diphtheria bacillus, typhoid bacillus, paratyphoid bacillus, and escherichia coli, the water extract useful only for Salmonella typhi.
3. Muscle relaxation: senna can block acetylcholine at the motor nerve terminals and skeletal joints, so that muscle relaxation.
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