L-5-methyltetrahydrofolate calcium is the active folate form, supplied as a white powder and specified on the L-5-MTHF assay and the calcium content. It is used at a very low dose in capsules, tablets and stick packs.
| Product Name | Calcium L-5-Methyltetrahydrofolate |
| Active Marker | L-5-MTHF calcium salt; assay as declared |
| Source | Synthetic or fermentation-derived |
| Appearance | White powder |
| Form | Powder |
| Grade | Food grade |
| Assay | L-5-MTHF by HPLC; calcium content |
| Solubility / Particle Size | Water-soluble; low dose |
| Certification | ISO 9001 · ISO 22000 · HACCP · Halal |
| MOQ | 1 kg |
| Packaging | 1 kg foil bag / 25 kg fibre drum |
| COA | Per batch; method, limit and result on one sheet |
| Shelf Life | 24 months, unopened |
| Storage | Cool, dry, protected from light |
| Delivery Time | 7 days |
| HS Code | 2934.99 (confirm with your broker) |
| CAS | 151533-22-1 |
L-5-methyltetrahydrofolate calcium is the active folate form, supplied as a white powder and specified on the L-5-MTHF assay and the calcium content. It is used at a very low dose in capsules, tablets and stick packs.
This page is for buyers comparing 5-MTHF quotations. It covers the salt form, the low-dose uniformity problem, the light and pH sensitivity and the batch tests that matter.
| Option | What it means | Best for |
|---|---|---|
| Calcium L-5-MTHF | Calcium salt; common in tablets and capsules | Low-dose tablets and capsules |
| Glucosamine L-5-MTHF | Glucosamine salt; different stability | Formulas where the calcium load matters |
| Folic acid | Synthetic folate; not the active form | Value-focused formulas with a different label |
The dose is very low, so the main formulation problem is uniformity. A few milligrams of 5-MTHF in a tablet blend have to be distributed evenly; a pre-diluted grade or a geometric dilution is the usual solution.
The molecule is sensitive to light, heat and low pH. An opaque bottle, a neutral pH and a cool drying step protect it. The calcium salt is water-soluble; in a stick pack, the taste and the colour are the other constraints.
L-5-MTHF is assayed by HPLC, and the calcium content is checked. Uniformity, moisture, heavy metals and microbiology are tested to the destination market's limits. The salt form and the assay method are stated on the COA.
Send the L-5-MTHF dose, the salt form, the dosage form and the market. The most common mistake is to compare quotations on the powder weight rather than the active assay; the second is to ignore the light and pH sensitivity in the packaging.
What is the difference between 5-MTHF and folic acid?
5-MTHF is the active, reduced form of folate; folic acid is the synthetic form. They are different label ingredients and different assays.
Why is the dose so low?
The active folate dose is measured in micrograms or a few milligrams. That makes blend uniformity the critical control.
How should it be stored?
Cool, dry and protected from light. The powder is sensitive to heat and low pH, so the packaging and the food matrix matter.
L-5-MTHF is sold here as a food ingredient. No disease or therapeutic claims are made or implied. The brand owner is responsible for the label and the permitted statements in the destination market.
Other products in this range:
| Vitamin D3 Powder | Vitamin D3 powder, IU/g |
| Biotin Powder | Biotin powder, HPLC assay |
| Vitamin K2 D3 Capsules | Vitamin K2 and D3 capsule |
| Multi-Mineral Tablets | 12 minerals in one tablet |
No therapeutic or disease claims are made or implied. Documentation is available on request.
Shaanxi Rainwood Biotech Co., Ltd. is a botanical extract and food-ingredient manufacturer based in Xi’an, China. Since 2006 we have supplied powders, extracts and mineral salts to supplement brands and food manufacturers in North America, Europe and Asia.
For a pure powder, the things that decide whether a drum is usable are the mesh or D90, blend uniformity, moisture and the pack. That is where we focus — the powder itself, not capsule, tablet or gummy OEM. We supply 1 kg foil bags for sampling and 25 kg fibre drums for production, with a moisture barrier where the material needs it.
Every batch is released against a written specification. The COA states the method, the release limit and the batch result; the TDS, allergen statement, GMO statement and certificate copies are available before the order. Third-party testing by SGS or Eurofins can be arranged on request.
• ISO 9001 / ISO 22000 / HACCP / Halal-certified site
• Batch records and retention samples for traceability
• 1 kg sample, 25 kg production pack, 7-day lead time for stock grades
This page covers L-5-Methyltetrahydrofolate Calcium in bulk powder form; the current COA and TDS are available on request.
Certificates: ISO 9001 · ISO 22000 · HACCP · NSF · USDA Organic · EU Organic · Halal · IQNET
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