| Product Name | Urolithin B Powder |
| Grade | Food Grade |
| Certification | HACCP/ISO 22000/HALAL/IS0 9001 |
| Specification | 50%Pure |
| Appearance | Yellow powder |
| Delivery Time | 7 days |
| Nutrient Content | Vegan, Gluten-Free, Non-GMO, Natural |
| Shelf Life | 2 Years |
| Storage | Cool Dry Place |
Urolithin B is a high-purity (≥95%-99.74%) white to off-white crystalline powder with the molecular formula C₁₃H₈O₃ and a molecular weight of 212.20 g/mol. As a natural metabolite derived from ellagitannins—found in pomegranates, berries, and nuts—Urolithin B is produced by gut microbiota and exhibits potent anti-inflammatory, antioxidant, and muscle-regulating properties.
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High Purity and Regulatory Compliance
Urolithin B powder is available in ≥98% HPLC purity with rigorous quality control (e.g., heavy metals ≤10 ppm, microbial limits ≤1000 CFU/g) . Suppliers hold certifications like ISO, GMP, Kosher, and Halal, ensuring compliance with pharmaceutical and food-grade standards . While UB itself is not yet GRAS-approved, its synthetic production (non-animal origin) aligns with clean-label trends, enabling market entry in dietary supplements and functional foods .
Unique Metabolic Profile and Bioactivity
Gut Microbiota-Derived Efficacy: UB is a metabolite of ellagitannins (e.g., from pomegranates, walnuts) produced by gut bacteria. Unlike its precursor ellagic acid, UB exhibits enhanced bioavailability (plasma levels up to 3–4 days post-ingestion) and direct interaction with cellular pathways .
Multi-Target Mechanisms:
AMPK Activation: UB regulates energy homeostasis by activating AMPK, a key enzyme in metabolic disorders like obesity and diabetes .
NF-κB Inhibition: Suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6) and oxidative stress, with IC₅₀ values for DPPH radical scavenging at 17.77 μg/mL .
Muscle Regeneration: Preclinical studies show UB promotes lean muscle growth by inhibiting muscle catabolism and enhancing mitochondrial function .
Cost-Effective and Scalable Production
Synthetic vs. Fermentation Routes: UB is produced via chemical synthesis (e.g., from α-resorcyclic acid) or microbial fermentation (e.g., E. coli strains), yielding ≥98% purity at $150–$300/kg (wholesale) .
Waste Valorization: Fermentation processes utilize renewable feedstocks (e.g., glucose), reducing environmental impact compared to plant extraction .
Bulk Availability: Suppliers offer bulk packaging (1 kg/bag, 25 kg/drum) with global shipping logistics .
Safety and Tolerability
Low Toxicity: Oral LD₅₀ >2 g/kg in rodents, with minimal skin/eye irritation. Clinical trials report no adverse effects at doses up to 300 mg/day .
GRAS Pending: Synthetic production ensures compliance with dietary restrictions (Kosher/Halal) and reduces allergenic risks .
Emerging Applications and Technological Innovation
Personalized Nutrition: AI-formulated supplements combining UB with probiotics target gut dysbiosis, tapping into the $25B personalized health market .
Precision Agriculture: UB enhances plant stress resistance (e.g., drought tolerance) in smart farming systems, aligning with the $8B agritech industry .
Nanodelivery Systems: Liposomal formulations (e.g., LipiSperse) improve UB bioavailability by 3-fold and reduce systemic side effects .
Market Growth and Strategic Positioning
High-Growth Market: The global ellagitannin-derived ingredient market is projected to reach $1.2B by 2030, driven by demand for natural anti-inflammatory and metabolic health solutions .
Global Reach: Suppliers in China and Europe dominate production, with North America and Asia-Pacific emerging as key markets for medical and cosmetic applications .
Intellectual Property: Patents covering UB’s use in weight management (US 9,901,596) and microbial production ensure competitive barriers .
Established in 2006, we are a certified OEM/ODM manufacturer specializing in premium health supplements. Holding NSF-GMP,HACCP, ISO 22000, USDA Organic, EU Organic, Halal, and FDA certifications, our facility integrates advanced technologies for tablet, capsule, powder, gummy, and softgel production. From formulation to packaging, we provide full-cycle solutions with strict quality protocols, including raw material traceability, third-party lab testing, and Halal-compliant dedicated lines. Serving global markets including North America, Europe, and Asia, we prioritize sustainability through eco-friendly processes and transparent labeling. With 19+ years of expertise, we empower brands to deliver scientifically validated, certification-backed nutraceuticals tailored to diverse regulatory and cultural requirements 
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