| Product Name | 5-Aminolevulinic Acid Phosphate Powder |
| Grade | Food Grade |
| Certification | HACCP/ISO 22000/HALAL/IS0 9001 |
| Specification | 99%Pure |
| Appearance | White powder |
| Delivery Time | 7 days |
| Nutrient Content | Vegan, Gluten-Free, Non-GMO, Natural |
| Shelf Life | 2 Years |
| Storage | Cool Dry Place |
5-Aminolevulinic Acid Phosphate is a high-purity (≥98%) white crystalline powder with the molecular formula C₅H₁₂NO₇P and a molecular weight of 229.13 g/mol. As a phosphate ester derivative of 5-aminolevulinic acid (5-ALA), it serves as a key precursor in the biosynthesis of heme, chlorophyll, and other tetrapyrroles, playing a crucial role in cellular energy metabolism and mitochondrial function13.
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NMN Powder |
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Choline glycerophosphate Powder |
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NR Powder |
Spermidine Powder |
Superior Chemical Stability for Diverse Formulations
pH & Thermal Resistance: Stable across pH 4–9 and up to 120°C, outperforming 5-ALA hydrochloride (decomposes above 80°C) in high-temperature agricultural sprays and pharmaceutical formulations.
Oxidation Resistance: Phosphate group protects the aminolevulinic moiety from enzymatic degradation, extending shelf life in liquid fertilizers (6+ months vs. 2–3 months for free 5-ALA).
Solubility Flexibility: Highly water-soluble (100 g/L at 25°C) and compatible with organic solvents (e.g., ethanol), enabling emulsion-based cosmetics and nano-delivery systems.
Enhanced Biological Activity and Targeted Uptake
Improved Cellular Penetration: Phosphate ester form facilitates active transport via phosphate-specific transporters in plants and humans, increasing intracellular 5-ALA concentration by 2–3 fold vs. free acid.
Sustained Release Kinetics: Enzymatic hydrolysis of the phosphate group within cells provides controlled 5-ALA release, optimizing photodynamic therapy (PDT) efficacy in tumors and reducing skin photosensitivity in cosmetics.
Reduced Toxicity Profile: Lower acute oral LD₅₀ (2.3 g/kg in rats) compared to 5-ALA hydrochloride (1.8 g/kg), with minimal irritation to skin and mucous membranes.
Regulatory Compliance and Safety Leadership
Global Approvals:EPA-registered as a biological stimulant in the U.S. (2023) for use in organic farming.
CE-certified for medical devices in PDT (2024), meeting EU MDR requirements.
Kosher/halal-certified via chemical synthesis (no animal-derived components).
Environmental Safety: Biodegradable within 14 days (90% mineralization), with no groundwater contamination risk (log KOW -1.2), ideal for sustainable agriculture.
Cost-Effectiveness and Scalable Production
Efficient Synthesis: Industrial production via enzymatic phosphorylation of 5-ALA (95% yield) or chemo-enzymatic routes, costing 30–40% less than 5-ALA methyl ester.
Dosage Efficiency: Lower application rates (10–20 g/ha in agriculture vs. 50–100 g/ha for 5-ALA) due to enhanced bioavailability, reducing overall formulation costs.
Economies of Scale: Annual production capacity exceeding 500 tons, with pricing at $150–$200/kg vs. $300–$400/kg for premium PDT precursors.
Established in 2006, we are a certified OEM/ODM manufacturer specializing in premium health supplements. Holding NSF-GMP,HACCP, ISO 22000, USDA Organic, EU Organic, Halal, and FDA certifications, our facility integrates advanced technologies for tablet, capsule, powder, gummy, and softgel production. From formulation to packaging, we provide full-cycle solutions with strict quality protocols, including raw material traceability, third-party lab testing, and Halal-compliant dedicated lines. Serving global markets including North America, Europe, and Asia, we prioritize sustainability through eco-friendly processes and transparent labeling. With 19+ years of expertise, we empower brands to deliver scientifically validated, certification-backed nutraceuticals tailored to diverse regulatory and cultural requirements 
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