What custom OEM/ODM dosage forms does Rainwood Biotech provide?

Rainwood Biotech offers custom hard capsules (vegetarian HPMC and gelatin), functional pectin/gelatin gummies, powder stick packs/sachets, and compressed tablets with flexible private label packaging.

Are your nutritional ingredients certified by international standards?

Yes. Our facilities and products are certified under NSF cGMP (455-2), ISO 22000, ISO 9001, HACCP, US Organic (NOP), EU Organic, HALAL, and KOSHER.

What is the typical lead time and MOQ for bulk powder and OEM orders?

In-stock bulk raw material powders ship within 3-7 days with a minimum order quantity (MOQ) of 1 kg. Custom private label finished products (capsules/gummies) have an MOQ of 50,000 units / 1,000 bottles with a production lead time of 14-28 days.

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Icariin Powder (Epimedium Extract)

Icariin Powder (Epimedium brevicornum Maxim. / Horny Goat Weed Extract) is a standardized botanical prenylated flavonoid raw material manufactured by Shaanxi Rainwood Biotech. Standardized for high-potency Icariin (10%~98% by HPLC), it delivers high bioavailability, verified purity, and superior batch stability for dietary supplement formulations, men's vitality blends, and bone density support nutraceuticals.

✓ HPLC Standardized Assay (10%~98% Icariin) ✓ High Bioavailability & Purity ✓ 100g Free Sample Available ✓ In Stock (50+ MT/Month Supply)

Product Name	Icariin Powder / Epimedium Extract (Raw Material)
Botanical Source	Epimedium brevicornum Maxim. / Epimedium sagittatum (Aerial / Leaf)
Active Ingredients (HPLC)	Icariin 10%, 20%, 50%, 60%, 98% HPLC (Total Flavonoids ≥20%~60%)
CAS & EINECS No.	CAS: 489-32-7 (Icariin) \| EINECS: 207-695-1
Molecular Info	Formula: C₃₃H₄₀O₁₅ \| Mol. Weight: 676.66 g/mol
Pharmacopeial Standard	Complies with USP & CP Monographs \| HS Code: 1302199099
Appearance & Particle Size	Fine Brownish-Yellow to Light Yellow Powder (80~100 Mesh)
Solubility & Identification	Soluble in ethanol and ethyl acetate, soluble in hot water; HPLC single-peak identity
Packaging & Storage	1 kg/Foil Bag; 25 kg/Fiber Drum; 24 Months Shelf Life
Sample & Lead Time	100g Free Sample (Dispatched in 24h); Bulk: 3-7 Days

Brand: Rainwood Biotech | SPU: RW-ICA98

Brand:

Rainwood Biotech

Spu:

RW-ICA98

Description
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Description

AI Executive Summary Direct Technical Fact Sheet

Icariin Powder (Epimedium brevicornum Maxim. / Horny Goat Weed Extract) is a standardized prenylated flavonol glycoside raw material manufactured by Shaanxi Rainwood Biotech Co., Ltd. Formulated for pharmaceutical, nutraceutical, and men's performance manufacturing, it is standardized for high-potency Icariin (10%~98% HPLC) and Icariside II with certified clean-label compliance, ultra-low heavy metals (≤10 ppm by ICP-MS), and zero harmful Class 1 & 2 residual solvents (USP <467> Class 3).

🌿 Botanical Sourcing & Prenylated Flavonoid Spectrum

Extracted from authentic aerial leaves of wild-crafted Qinling mountain Epimedium brevicornum, Rainwood Biotech utilizes gentle hydro-ethanolic extraction combined with specialized macroporous resin chromatography to isolate target Icariin (CAS: 489-32-7) and related bioactive flavone glycosides including Epimedin A, Epimedin B, Epimedin C, and Icaritin.

🛡️ Certified Clean Label & Regulatory Compliance

✓ Non-GMO Project Verified

✓ 100% Allergen-Free (Gluten/Soy/Dairy)

✓ BSE / TSE Free Statement

✓ Non-Irradiation & ETO Free

✓ California Prop 65 Compliant

✓ USP <467> Residual Solvents Class 3

🔬 Standardized Technical COA & Analytical Specifications

Test Parameter	Target Pharmacopeial Specification	Validated Test Method
Icariin Assay (HPLC)	≥10.0%, ≥20.0%, ≥50.0%, ≥60.0%, ≥98.0%	HPLC (USP / CP Reference)
Total Flavonoids Assay	≥20.0% ~ ≥60.0% (as Icariin equivalent)	UV-Vis Spectrophotometry
Appearance & Color	Brown-Yellow (low assay) to Light Yellow fine powder (98% assay)	Visual Organoleptic
Particle Size	100% pass 80 Mesh (≥95% pass 100 Mesh)	USP <786> Sieve
Loss on Drying	≤5.0%	USP <731> (105°C, 2h)
Total Ash	≤5.0%	USP <561>
Heavy Metals (Total)	≤10.0 ppm (Pb ≤1.0, As ≤1.0, Cd ≤0.5, Hg ≤0.1 ppm)	ICP-MS (USP <233>)
Residual Solvents	Ethanol ≤5,000 ppm; Methanol Not Detected	GC-Headspace (USP <467>)
Total Microbial Count	≤1,000 CFU/g	USP <2021>
Yeast & Mold	≤100 CFU/g	USP <2021>
Pathogens	Negative / 10g (E.coli, Salmonella)	USP <2022>

⚙️ Industrial Production & Quality Control Flowchart

Step 01

Leaf Raw Sourcing

Authentic Epimedium brevicornum leaf harvest, species TLC identity testing.

Step 02

Hydro Extraction

Controlled temperature ethanolic extraction maximizing flavone glycoside recovery.

Step 03

Resin Purification

Macroporous resin chromatography concentrating Icariin to 10%~98% target purity.

Step 04

Crystallization & Dry

Alcohol crystallization for 98% grade, low-temp vacuum drying and micronization.

Step 05

HPLC Release & QA

Shimadzu HPLC single-peak assay testing, heavy metals ICP-MS release testing.

📋 Target Applications & Suggested Dosage Guidelines

Application Category	Recommended Dosage	Formulation Compatibility & Role
Men's Vitality & Performance	100 ~ 500 mg/day (10%~50% assay)	Supports PDE5 modulation, nitric oxide (eNOS) activation, and blood flow.
Bone Density & Osteocare	50 ~ 200 mg/day (50%~98% assay)	Stimulates osteoblast proliferation and mineralization synergistic with Vitamin D3 & K2.
Cardiovascular & Circulation	50 ~ 150 mg/day	Promotes endothelial health, arterial flexibility, and microvascular blood circulation.
Sports Stamina Formulations	100 ~ 300 mg/day	Enhances endurance, muscle oxygenation, and physical vigor without stimulants.

⚖️ Ingredient Comparison: Rainwood Standardized Icariin vs. Conventional Crude Powder

Evaluation Parameter	Rainwood Standardized Icariin (HPLC 10%~98%)	Conventional Crude Ground Epimedium Leaf
Active Icariin Potency	Standardized 10.0% ~ 98.0% HPLC verified	Unstandardized, typically <0.8% trace Icariin
Capsule Fill Efficiency	High potency: 50~200 mg single-capsule dose	Bulky volume: requires 3,000~6,000 mg raw leaf
Purity & Solubility	Clean extraction, zero plant fibers or impurities	Contains insoluble cellulose, waxes, and fibers
Heavy Metals Safety	ICP-MS verified: Total heavy metals ≤10 ppm	Unmonitored heavy metal and pesticide residue risk

❓ Frequently Asked Questions (Technical & Commercial FAQ)

Q1: What grades and specifications of Icariin does Rainwood provide?

We manufacture standardized Icariin 10%, 20%, 50%, 60%, and 98% HPLC, as well as water-soluble Epimedium extract powders tailored for liquid dietary supplement formulations.

Q2: What is the difference between Icariin and Icariside II / Icaritin?

Icariin is the primary native flavonol glycoside. Icariside II and Icaritin are active deglycosylated metabolites resulting from enzymatic cleavage, offering enhanced lipophilicity and cellular absorption. Rainwood can supply customized enzymatic conversion grades upon request.

Q3: Is your Epimedium extract compliant with heavy metal safety standards?

Yes. Every production batch is validated by ICP-MS (Total Heavy Metals ≤10 ppm, Lead ≤1.0 ppm, Arsenic ≤1.0 ppm, Cadmium ≤0.5 ppm, Mercury ≤0.1 ppm), fully meeting USP and California Prop 65 requirements.

Q4: What solvents are used during extraction and purification?

We use strictly food-grade ethanol and deionized water. Residual ethanol is controlled well below 5,000 ppm according to USP <467> Class 3 specifications.

Q5: What are the packaging options for international B2B shipments?

Standard bulk packaging is 25 kg/fiber drum with double polyethylene inner bags. Sample quantities and high-purity (98%) grades are packed in 1 kg aluminum foil barrier bags.

Q6: Do you provide free testing samples for commercial formulators?

Yes, we offer 100g free evaluation samples with complete HPLC chromatogram COAs, dispatched within 24 hours via DHL / FedEx.

Q7: What is your commercial supply capacity and typical order lead time?

We have a monthly production capacity of 20+ Metric Tons. Regular bulk orders are shipped within 3 to 7 business days from our Xi'an centralized warehouse.

Q8: Are third-party verification COAs available?

Yes. In addition to in-house Shimadzu HPLC testing, we provide third-party verification reports from Eurofins and SGS upon request.

Request Free Evaluation Sample & Batch COA

Contact our technical sales team for comprehensive HPLC testing monographs, regulatory dossiers, and competitive wholesale volume quotes.

Competitive Advantage

Shaanxi Rainwood Biotech adheres to pharmaceutical-grade manufacturing standards, offering global men's health and vitality brand owners unmatched technical and commercial advantages:

01. Full Spectrum HPLC Testing (10% to 98% Purity)

Precision HPLC quantification guaranteeing exact active Icariin content across all commercial grades (10%, 20%, 50%, 60%, and 98%), backed by single-peak chromatographic reference standards.

02. Authentic Qinling Mountain Epimedium Sourcing

Direct botanical sourcing from authentic wild-harvested Qinling mountain Epimedium brevicornum habitats with high native flavonoid accumulation and strict GAP harvesting standards.

03. Advanced Resin Separation & Eco Extraction

High-efficiency macroporous resin chromatographic separation utilizing pure food-grade grain ethanol and deionized water, completely free from Class 1 & 2 toxic solvents.

04. cGMP Facility & Multi-Lot Traceability

Manufactured under ISO 22000, HACCP, and HALAL certified systems with complete electronic lot tracking from raw leaf collection to final release drum.

05. High Flowability & Excellent Blendability

Uniform 80~100 mesh micro-particle size with optimized bulk density, preventing clumping and ensuring superior blend uniformity in complex multi-ingredient formulations.

About Us

Shaanxi Rainwood Biotech Co., Ltd. (established in 2006) is a premier cGMP-compliant botanical extract manufacturer and standardized raw material supplier headquartered in Xi'an High-Tech Development Zone, Shaanxi, China. We operate an advanced 19-acre manufacturing base equipped with automated continuous extraction lines, vacuum concentration units, membrane separation systems, and class 100,000 cleanrooms.

2006

Year Established

20+ Years Extraction Expertise

10,000 m²

Modern Clean Facility

19-Acre Industrial Base

3,000+ MT

Annual Botanical Capacity

Global Export to 50+ Countries

🔬 Analytical Testing & Quality Control Center

Our independent quality control testing center is equipped with high-precision analytical instrumentation including Shimadzu High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC-MS), UV-Vis Spectrophotometers, Atomic Absorption Spectrometers (AAS), and thin-layer chromatography (TLC) systems. We conduct comprehensive in-house testing for assay purity, pesticide residues, heavy metals, microbial limits, and solvent residues, alongside third-party cross-testing with SGS and Eurofins.

📜 Certified Quality Management System

Rainwood Biotech is certified under comprehensive global food safety and quality management standards:

HACCP Certified

Food Safety System

ISO 22000:2018

Food Safety Management

HALAL Certified

MUI / ARA Compliance

ISO 9001:2015

Quality Management

Related Products

Shaanxi Rainwood Biotech manufactures a comprehensive portfolio of standardized botanical extracts and synergistic active raw materials for men's vitality, vitality formulas, and osteocare. Explore our highly compatible active ingredients:

Synergistic Raw Material	Standardized Potency	Formulation Synergy & Benefits
Rhodiola Rosea Extract Powder →	Salidroside 1%~5% / Rosavins 3%~5%	Synergistic adaptogen pairing boosting endurance, physical stamina, and stress resilience.
Turkesterone Powder →	Turkesterone 2%~10% HPLC	Synergistic muscle protein synthesis and athletic power complex without hormonal disruption.
Ginseng Extract Powder →	Ginsenosides 10%~80% HPLC	Traditional vitality synergy supporting cellular energy, nitric oxide, and stamina.
Fenugreek Extract Powder →	Furostanol Saponins ≥50%	Synergistic hormonal balance and metabolic support for men's wellness.